Samtskhe-Javakheti (Georgian: სამცხე-ჯავახეთი, Samcxe-Javaxeti, pronounced [sɑmtsʰxɛ dʒɑvaxɛtʰi]), is a region (Georgian: Mkhare) formed in the 1995 in southern Georgia from the historical provinces of Meskheti (Samtskhe), Javakheti and Tori (Borjomi gorge). Akhaltsikhe is its capital. The region comprises six administrative districts: Akhaltsikhe, Adigeni, Aspindza, Borjomi, Akhalkalaki and Ninotsminda. There are 5 town, 6 townlets, 67 community and village sakrebulos (assemblies), and 268 villages in the region. Samtskhe-Javakheti is bordered by the regions of Adjara to the west, Guria and Imereti to the north, Shida Kartli and Kvemo Kartli to the north-east and to the east, and by Armenia and Turkey to the south and southwest.
The Baku-Tbilisi-Ceyhan oil pipeline, the South Caucasus natural gas pipeline, and the Kars–Tbilisi–Baku railway (under construction) pass through the region.